Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance

Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance

Abstract Cancer cells in secondary tumors are found to form metastases more efficiently as compared to their primary tumor counterparts. This is partially due to the unfavorable microenvironments encountered by metastasizing cancer cells that result in the survival of a more metastatic phenotype fro...

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Bibliographic Details
Main Authors: Kuan Jiang, Su Bin Lim, Jingwei Xiao, Doorgesh Sharma Jokhun, Menglin Shang, Xiao Song, Pan Zhang, Lanfeng Liang, Boon Chuan Low, G.V. Shivashankar, Chwee Teck Lim
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
cancer metastasis
circulating tumor cells
mechanical damage
nuclear mechanics
physical microenvironment
Online Access:https://doi.org/10.1002/advs.202201663

Internet

https://doi.org/10.1002/advs.202201663

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