Identification of the SlmA active site responsible for blocking bacterial cytokinetic ring assembly over the chromosome.

Bacterial cells use chromosome-associated division inhibitors to help coordinate the processes of DNA replication and segregation with cytokinesis. SlmA from Escherichia coli, a member of the tetracycline repressor (TetR)-like protein family, is one example of this class of regulator. It blocks the...

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Bibliographic Details
Main Authors: Hongbaek Cho, Thomas G Bernhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3573117?pdf=render