Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine

Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine

Abstract Background The generation of induced pluripotent stem cells has opened the field of study for stem cell research, disease modeling and drug development. However, the epigenetic signatures present in somatic cells make cell reprogramming still an inefficient process. This epigenetic memory c...

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Bibliographic Details
Main Authors: Alain Aguirre-Vázquez, Fabiola Castorena-Torres, Beatriz Silva-Ramírez, Katia Peñuelas-Urquides, María Elena Camacho-Moll, Luis A. Salazar-Olivo, Iván Velasco, Mario Bermúdez de León
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Stem Cell Research & Therapy
Subjects:
Hydralazine
Valproic acid
iPSC
Fibroblasts
Reprogramming
Genes
Online Access:https://doi.org/10.1186/s13287-023-03268-w

Internet

https://doi.org/10.1186/s13287-023-03268-w

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