Automated Prognosis Marker Assessment in Breast Cancers Using BLEACH&STAIN Multiplexed Immunohistochemistry

Automated Prognosis Marker Assessment in Breast Cancers Using BLEACH&STAIN Multiplexed Immunohistochemistry

Prognostic markers in routine clinical management of breast cancer are often assessed using RNA-based multi-gene panels that depend on fluctuating tumor purity. Multiplex fluorescence immunohistochemistry (mfIHC) holds the potential for an improved risk assessment. To enable automated prognosis mark...

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Bibliographic Details
Main Authors: Tim Mandelkow, Elena Bady, Magalie C. J. Lurati, Jonas B. Raedler, Jan H. Müller, Zhihao Huang, Eik Vettorazzi, Maximilian Lennartz, Till S. Clauditz, Patrick Lebok, Lisa Steinhilper, Linn Woelber, Guido Sauter, Enikö Berkes, Simon Bühler, Peter Paluchowski, Uwe Heilenkötter, Volkmar Müller, Barbara Schmalfeldt, Albert von der Assen, Frank Jacobsen, Till Krech, Rainer H. Krech, Ronald Simon, Christian Bernreuther, Stefan Steurer, Eike Burandt, Niclas C. Blessin
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
breast cancer
prognosis markers
multiplex fluorescence immunohistochemistry
artificial intelligence
Online Access:https://www.mdpi.com/2227-9059/11/12/3175

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https://www.mdpi.com/2227-9059/11/12/3175

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