Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma.

Circulating tumor cells (CTCs) are cells shed from solid tumors into circulation and have been shown to be prognostic in the setting of metastatic disease. These cells are obtained through a routine blood draw and may serve as an easily accessible marker for monitoring treatment effectiveness. Becau...

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Bibliographic Details
Main Authors: Robert J Torphy, Christopher J Tignanelli, Joyce W Kamande, Richard A Moffitt, Silvia G Herrera Loeza, Steven A Soper, Jen Jen Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3929698?pdf=render