Integrating protein localization with automated signaling pathway reconstruction

Integrating protein localization with automated signaling pathway reconstruction

Abstract Background Understanding cellular responses via signal transduction is a core focus in systems biology. Tools to automatically reconstruct signaling pathways from protein-protein interactions (PPIs) can help biologists generate testable hypotheses about signaling. However, automatic reconst...

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Bibliographic Details
Main Authors: Ibrahim Youssef, Jeffrey Law, Anna Ritz
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Signaling pathways
Biological networks
Protein-protein interaction
Protein localization
Online Access:https://doi.org/10.1186/s12859-019-3077-x

Internet

https://doi.org/10.1186/s12859-019-3077-x

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