Utilizing two-dimensional monolayer and three-dimensional spheroids to enhance radiotherapeutic potential by combining gold nanoparticles and docetaxel

Abstract Background Much in vitro research on the applicability of gold nanoparticles (GNPs) in cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve this, we explored the effect of the combination of GNPs and docetaxel (DTX) with radiotherapy (RT) in a more complex...

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Bibliographic Details
Main Authors: Kyle Bromma, Wayne Beckham, Devika B. Chithrani
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cancer Nanotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12645-023-00231-5