DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration

Alterations in environmentally sensitive epigenetic mechanisms (e.g., DNA methylation) influence axonal regeneration in the spinal cord following sharp injury. Conventional DNA methylation detection methods using sodium bisulphite treatment do not distinguish between methylated and hydroxymethylated...

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Bibliographic Details
Main Authors: Andy Madrid, Laura E. Borth, Kirk J. Hogan, Nithya Hariharan, Ligia A. Papale, Reid S. Alisch, Bermans J. Iskandar
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2020.1786320