Up-regulation of SLC27A2 suppresses the proliferation and invasion of renal cancer by down-regulating CDK3-mediated EMT

Abstract Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant tumors of the urinary system. Distant metastasis is the leading cause of poor prognosis in ccRCC. However, ccRCC is found poorly responsitive to radiotherapy and chemotherapy. Effective therapeutic strategies for it...

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Bibliographic Details
Main Authors: Ning Xu, Wen Xiao, Xiangui Meng, Weiquan Li, Xuegang Wang, Xiaoping Zhang, Hongmei Yang
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01145-8