L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro

Summary: L-lactate has energetic and signaling properties, and its availability is modulated by activity-dependent stimuli, which also regulate adult hippocampal neurogenesis. Studying the effects of L-lactate on neural precursor cells (NPCs) in vitro, we found that L-lactate is pro-proliferative an...

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Bibliographic Details
Main Authors: Alexandra Pötzsch, Sara Zocher, Stefanie N. Bernas, Odette Leiter, Annette E. Rünker, Gerd Kempermann
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000948