The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across Pseudomonas species.

Competitive bacteria-bacteriophage interactions have resulted in the evolution of a plethora of bacterial defense systems preventing phage propagation. In recent years, computational and bioinformatic approaches have underpinned the discovery of numerous novel bacterial defense systems. Anti-phage s...

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Bibliographic Details
Main Authors: Elliot Macdonald, Rosanna Wright, James P R Connolly, Henrik Strahl, Michael Brockhurst, Stineke van Houte, Tim R Blower, Tracy Palmer, Giuseppina Mariano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010784