Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries

Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries

Abstract Mounting attention has been focused on defects of the autophagy-lysosomal pathway in sepsis, however, the precise mechanisms governing the autophagy-lysosomal process in sepsis are poorly known. We have previously reported that Erbin deficiency aggravated the inflammatory response and organ...

Full description

Bibliographic Details
Main Authors: Qing Fang, Guoqing Jing, Ying Zhang, Hongyu Wang, Huan Luo, Yun Xia, Qiyan Jin, Yuping Liu, Jing Zuo, Cheng Yang, Xiaodong Zhang, Shi Liu, Xiaojing Wu, Xuemin Song
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Erbin
Autophagy
Lysosome
TFEB
Sepsis
Online Access:https://doi.org/10.1186/s12967-023-04796-y

Internet

https://doi.org/10.1186/s12967-023-04796-y

Similar Items