Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries
Abstract Mounting attention has been focused on defects of the autophagy-lysosomal pathway in sepsis, however, the precise mechanisms governing the autophagy-lysosomal process in sepsis are poorly known. We have previously reported that Erbin deficiency aggravated the inflammatory response and organ...
Main Authors: | Qing Fang, Guoqing Jing, Ying Zhang, Hongyu Wang, Huan Luo, Yun Xia, Qiyan Jin, Yuping Liu, Jing Zuo, Cheng Yang, Xiaodong Zhang, Shi Liu, Xiaojing Wu, Xuemin Song |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-023-04796-y |
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