Fuse your mitochondria, lose appetite: an anorexic, anti‐obesity sphingolipid

Aberrant production of ceramides, the precursors of complex sphingolipids, is a hallmark of obesity and strongly linked to metabolic dysfunction (Meikle and Summers 2017). Ceramides are formed by recycling or de novo synthesis from sphingosine and a fatty acid side chain moiety. The side chain lengt...

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Bibliographic Details
Main Authors: Carolin Muley, Alexander Bartelt
Format: Article
Language:English
Published: Springer Nature 2021-08-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202114618