Nanoparticles alleviate non-alcoholic steatohepatitis via ER stress sensor-mediated intestinal barrier damage and gut dysbiosis

Nanoparticles alleviate non-alcoholic steatohepatitis via ER stress sensor-mediated intestinal barrier damage and gut dysbiosis

IntroductionThe gut microbiota plays an important role in the development of non-alcoholic steatohepatitis (NASH), but the underlying mechanism is unclear. It has been found that the transcription factor XBP1s plays an important role in regulating inflammation and lipid metabolism and maintaining th...

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Bibliographic Details
Main Authors: Manman Zhu, Yong Cheng, Yue Tang, Shuojiao Li, Peng Rao, Guiyang Zhang, Lei Xiao, Jiatao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
non-alcoholic steatohepatitis
endoplasmic reticulum stress
X-box binding protein 1
gut microbiota
lipopolysaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1271835/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1271835/full

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