Cell-Cycle Synchronization Prior to Radiotherapy: A Mathematical Model of the Use of Gemcitabine on Melanoma Xenografts
Radiotherapy can differentially affect the phases of the cell cycle, possibly enhancing suppression of tumor growth, if cells are synchronized in a specific phase. A model is designed to replicate experiments that synchronize cells in the S phase using gemcitabine before radiation at various doses,...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-02-01
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Series: | AppliedMath |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-9909/4/1/10 |