Cell-Cycle Synchronization Prior to Radiotherapy: A Mathematical Model of the Use of Gemcitabine on Melanoma Xenografts

Radiotherapy can differentially affect the phases of the cell cycle, possibly enhancing suppression of tumor growth, if cells are synchronized in a specific phase. A model is designed to replicate experiments that synchronize cells in the S phase using gemcitabine before radiation at various doses,...

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Bibliographic Details
Main Authors: Frederika Rentzeperis, Benjamin Coleman, Dorothy Wallace
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:AppliedMath
Subjects:
Online Access:https://www.mdpi.com/2673-9909/4/1/10