Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3. Model systems allow the identification and testing of new therapeutic targets. Here, w...

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Bibliographic Details
Main Authors: Uta Katharina Radine, Valéria Bumiller-Bini Hoch, Angelica B. Winter Boldt, Detlef Zillikens, Ralf J. Ludwig, Christoph M. Hammers, Matthias Klinger, Jennifer E. Hundt
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
pemphigus
human skin organ culture
desmosome
electron microscopy
desmoglein
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.997387/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.997387/full

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