The Role of Osteopontin as a Diagnostic and Prognostic Biomarker in Sepsis and Septic Shock

The Role of Osteopontin as a Diagnostic and Prognostic Biomarker in Sepsis and Septic Shock

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host-response to infections. Osteopontin (OPN) is an extracellular matrix protein involved in the inflammatory response. Our aim was to evaluate the diagnostic and prognostic performance in sepsis of a single OPN determination i...

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Bibliographic Details
Main Authors: Luigi Mario Castello, Marco Baldrighi, Luca Molinari, Livia Salmi, Vincenzo Cantaluppi, Rosanna Vaschetto, Greta Zunino, Marco Quaglia, Mattia Bellan, Francesco Gavelli, Paolo Navalesi, Gian Carlo Avanzi, Annalisa Chiocchetti
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Osteopontin
biomarkers
sepsis
Emergency Department
diagnosis
risk stratification
prognosis
Online Access:https://www.mdpi.com/2073-4409/8/2/174

Internet

https://www.mdpi.com/2073-4409/8/2/174

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