A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from <i>Xylopia vielana</i> Targeting B-Raf Kinase

A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from <i>Xylopia vielana</i> Targeting B-Raf Kinase

Compounds derived from plants have several anticancer properties. In the current study, one guaiane-type sesquiterpene dimer, vieloplain F, isolated from <i>Xylopia vielana</i> species, was tested against B-Raf kinase protein (PDB: 3OG7), a potent target for melanoma. A comprehensive in...

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Bibliographic Details
Main Authors: Syed Shams ul Hassan, Syed Qamar Abbas, Fawad Ali, Muhammad Ishaq, Iqra Bano, Mubashir Hassan, Hui-Zi Jin, Simona G. Bungau
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
guaiane dimer
melanoma
molecular docking
ADMET
MM-GBSA
Online Access:https://www.mdpi.com/1420-3049/27/3/917

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https://www.mdpi.com/1420-3049/27/3/917

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