A pH- and Bioreducible Cationic Copolymer with Amino Acids and Piperazines for Adenovirus Delivery
Adenoviruses (Ads) are attractive nonviral vectors and show great potential in cancer gene therapy. However, inherent properties of Ads, including immunogenicity, nonspecific toxicity, and coxsackie and adenovirus receptor (CAR)-dependent cell uptake, limit their clinical use. To surmount these issu...
| Autors principals: | , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
MDPI AG
2022-03-01
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| Col·lecció: | Pharmaceutics |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/1999-4923/14/3/597 |