Case Report: Potential Predictive Value of MMR/MSI Status and PD-1 Expression in Immunotherapy for Urothelial Carcinoma

Case Report: Potential Predictive Value of MMR/MSI Status and PD-1 Expression in Immunotherapy for Urothelial Carcinoma

Immune checkpoint inhibitors (ICIs) have shown encouraging outcomes against Lynch syndrome (LS)-associated colorectal cancer (CRC) and endometrial cancer with mismatch repair deficient/microsatellite instability–high (dMMR/MSI-H). However, there is as yet no clarity on the safety and efficacy of imm...

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Bibliographic Details
Main Authors: Yu-Ting Ma, Yan Li, Li Yan, Fang Hua, Dong-Guan Wang, Guo-Ying Xu, Hong-Lan Yang, Ying-Jie Xue, Ye-Jun Qin, Dan Sha, Hao Ning, Miao-Qing Zhao, Zhi-Gang Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Pathology and Oncology Research
Subjects:
immunotherapy
microsatellite instability
immune checkpoint inhibitors
urothelial carcinoma
lynch syndrome
PD-1/PD-L1
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610638/full

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https://www.por-journal.com/articles/10.3389/pore.2022.1610638/full

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