Shared effects of genetic and intrauterine and perinatal environment on the development of metabolic syndrome.

Genetic and environmental factors, including the in utero environment, contribute to Metabolic Syndrome. Exposure to high fat diet exposure in utero and lactation increases incidence of Metabolic Syndrome in offspring. Using GLUT4 heterozygous (G4+/-) mice, genetically predisposed to Type 2 Diabetes...

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Bibliographic Details
Main Authors: Patricia M Vuguin, Kirsten Hartil, Michael Kruse, Harpreet Kaur, Chia-Lei Vivian Lin, Ariana Fiallo, Alan Scott Glenn, Avanee Patel, Lyda Williams, Yoshinori Seki, Ellen B Katz, Maureen J Charron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3656882?pdf=render