Protease-activated receptor-2: Role in asthma pathogenesis and utility as a biomarker of disease severity

PAR2, a receptor activated by serine proteases, has primarily pro-inflammatory roles in the airways and may play a role in asthma pathogenesis. PAR2 exerts its effects in the lungs through activation of a variety of airway cells, but also activation of circulating immune cells. There is evidence tha...

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Bibliographic Details
Main Authors: Vivek Dipak Gandhi, Nami Shrestha Palikhe, Harissios Vliagoftis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.954990/full