Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.

Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.

The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....

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Bibliographic Details
Main Authors: Jessica L Martin, Phillip A Yates, Radika Soysa, Joshua F Alfaro, Feng Yang, Kristin E Burnum-Johnson, Vladislav A Petyuk, Karl K Weitz, David G Camp, Richard D Smith, Phillip A Wilmarth, Larry L David, Gowthaman Ramasamy, Peter J Myler, Nicola S Carter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3937319?pdf=render

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http://europepmc.org/articles/PMC3937319?pdf=render

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