Engineering the Modular Receptor-Binding Proteins of <i>Klebsiella</i> Phages Switches Their Capsule Serotype Specificity
The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2021-06-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00455-21 |