Structural determinant of functionality in acyl lipid desaturases

Little is known about the structure-function relationship of membrane-bound lipid desaturases. Using a domain-swapping strategy, we found that the N terminus (comprising the two first transmembrane segments) region of Bacillus cereus DesA desaturase improves Bacillus subtilis Des activity. In additi...

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Bibliographic Details
Main Authors: Diego E. Sastre, Emilio Saita, Antonio D. Uttaro, Diego de Mendoza, Silvia G. Altabe
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341791