Invasive Pathobionts Contribute to Colon Cancer Initiation by Counterbalancing Epithelial Antimicrobial ResponsesSummary

Invasive Pathobionts Contribute to Colon Cancer Initiation by Counterbalancing Epithelial Antimicrobial ResponsesSummary

Background & Aims: Microbiota dysbiosis and mucosa-associated bacteria are involved in colorectal cancer progression. We hypothesize that an interaction between virulent pathobionts and epithelial defense promotes tumorigenesis. Methods: Chemical-induced CRC mouse model was treated with anti...

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Bibliographic Details
Main Authors: Linda Chia-Hui Yu, Shu-Chen Wei, Yi-Hsuan Li, Po-Yu Lin, Xin-Yu Chang, Jui-Ping Weng, Yin-Wen Shue, Liang-Chuan Lai, Jin-Town Wang, Yung-Ming Jeng, Yen-Hsuan Ni
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Colon Carcinoma
Gut Microbiome
Intracellular Microbes
Xenophagy
Reactive Oxygen Species
Organoids and Spheroids
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21001740

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http://www.sciencedirect.com/science/article/pii/S2352345X21001740

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