The AMPK/p27<sup>Kip1</sup> Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells
Once believed to solely function as a cyclin-dependent kinase inhibitor, p27<sup>Kip1</sup> is now emerging as a critical mediator of autophagy, cytoskeletal dynamics, cell migration and apoptosis. During periods of metabolic stress, the subcellular location of p27<sup>Kip1</sup...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/6/1430 |