Coordinated interplay between palmitoylation, phosphorylation and SUMOylation regulates kainate receptor surface expression

Coordinated interplay between palmitoylation, phosphorylation and SUMOylation regulates kainate receptor surface expression

Kainate receptors (KARs) are key regulators of neuronal excitability and synaptic transmission. KAR surface expression is tightly controlled in part by post-translational modifications (PTMs) of the GluK2 subunit. We have shown previously that agonist activation of GluK2-containing KARs leads to pho...

Full description

Bibliographic Details
Main Authors: Busra P. Yucel, Enaam M. Al Momany, Ashley J. Evans, Richard Seager, Kevin A. Wilkinson, Jeremy M. Henley
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
kainate receptors
post-translational modification
palmitoylation
S-acylation
phosphorylation
SUMOylation
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1270849/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1270849/full

Similar Items