Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle‐aged and older adults: A population‐based cohort study

Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle‐aged and older adults: A population‐based cohort study

Abstract Background Tissue factor is the main initiator of blood coagulation, and tissue factor pathway inhibitor (TFPI) is the primary inhibitor of the initiation of blood coagulation. The genetic variation of TFPI and the relation to venous thromboembolism (VTE), that is, venous thrombosis and pul...

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Bibliographic Details
Main Authors: Eric Manderstedt, Christina Lind‐Halldén, Christer Halldén, Johan Elf, Peter J. Svensson, Gunnar Engström, Olle Melander, Aris Baras, Luca A. Lotta, Bengt Zöller, for the Regeneron Genetics Center
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
blood coagulation
genetic variation
molecular epidemiology
thrombophilia
venous thromboembolism
Online Access:https://doi.org/10.1002/rth2.12842

Internet

https://doi.org/10.1002/rth2.12842

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