Immune Reconstitution Following Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis: A Review on Behalf of the EBMT Autoimmune Diseases Working Party

Immune Reconstitution Following Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis: A Review on Behalf of the EBMT Autoimmune Diseases Working Party

Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an abnormal immune response coordinated by T and B cells resulting in areas of inflammation, demyelination, and axonal loss. Disease-modifying treatments (DMTs) are available to dampen the inflammatory aggressio...

Full description

Bibliographic Details
Main Authors: Maria Teresa Cencioni, Angela Genchi, Gavin Brittain, Thushan I. de Silva, Basil Sharrack, John Andrew Snowden, Tobias Alexander, Raffaella Greco, Paolo A. Muraro
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
hematopoietic stem cell (HSC) transplantation
disease-modifying therapies (DMT)
immune reconstitution
immunological memory
vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.813957/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.813957/full

Similar Items