Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals

Production of chemicals by microbial fermentation is an economical alternative to chemical synthesis. Here the authors re-engineer the yeastS. cerevisiaeto produce the very long chain fatty alcohol docosanol by expressing a heterologous Mycobacteria fatty acid synthase and a specific fatty acid redu...

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Bibliographic Details
Main Authors: Tao Yu, Yongjin J. Zhou, Leonie Wenning, Quanli Liu, Anastasia Krivoruchko, Verena Siewers, Jens Nielsen, Florian David
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15587