The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling.

The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling.

FKBP52 and β-catenin have emerged in recent years as attractive targets for prostate cancer treatment. β-catenin interacts directly with the androgen receptor (AR) and has been characterized as a co-activator of AR-mediated transcription. FKBP52 is a positive regulator of AR in cellular and whole an...

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Bibliographic Details
Main Authors: Cheryl Storer Samaniego, Ji Ho Suh, Arundhati Chattopadhyay, Karen Olivares, Naihsuan Guy, Jeffrey C Sivils, Prasenjit Dey, Fumiaki Yumoto, Robert J Fletterick, Anders M Strom, Jan-Åke Gustafsson, Paul Webb, Marc B Cox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4514735?pdf=render

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http://europepmc.org/articles/PMC4514735?pdf=render

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