Angiopoietin-2 induces angiogenesis via exosomes in human hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is a highly vascularized solid tumor. Angiopoietin-2 (ANGPT2) has been described as an attractive target for antiangiogenic therapy. Exosomes are small extracellular vesicles secreted by most cell types an...

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Main Authors: Ji-yan Xie, Jin-xing Wei, Li-hong Lv, Qing-fang Han, Wei-bang Yang, Guo-lin Li, Pan-xia Wang, Shao-bin Wu, Jin-xin Duan, Wen-feng Zhuo, Pei-qing Liu, Jun Min
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell Communication and Signaling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12964-020-00535-8