Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition

Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition

A polyubiquitin comprises multiple covalently linked ubiquitins and recognizes myriad targets. Free or bound to ligands, polyubiquitins are found in different arrangements of ubiquitin subunits. To understand the structural basis for polyubiquitin quaternary plasticity and to explore the target reco...

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Bibliographic Details
Main Authors: Zhu Liu, Zhou Gong, Wen-Xue Jiang, Ju Yang, Wen-Kai Zhu, Da-Chuan Guo, Wei-Ping Zhang, Mai-Li Liu, Chun Tang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-06-01
Series:eLife
Subjects:
polyubiquitin
dynamics
ensemble
NMR
paramagnetic
Online Access:https://elifesciences.org/articles/05767

Internet

https://elifesciences.org/articles/05767

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