Discovery of alternative polyadenylation dynamics from single cell types

Discovery of alternative polyadenylation dynamics from single cell types

Alternative polyadenylation (APA) occurs in the process of mRNA maturation by adding a poly(A) tail at different locations, resulting increased diversity of mRNA isoforms and contributing to the complexity of gene regulatory network. Benefit from the development of high-throughput sequencing technol...

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Bibliographic Details
Main Authors: Congting Ye, Juncheng Lin, Qingshun Q. Li
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Alternative polyadenylation
3′ end sequencing
Cell type
Single-cell RNA-seq
Computational analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020300817

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http://www.sciencedirect.com/science/article/pii/S2001037020300817

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