Sox17 regulates liver lipid metabolism and adaptation to fasting.

Liver is a major regulator of lipid metabolism and adaptation to fasting, a process involving PPARalpha activation. We recently showed that the Vnn1 gene is a PPARalpha target gene in liver and that release of the Vanin-1 pantetheinase in serum is a biomarker of PPARalpha activation. Here we set up...

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Main Authors: Samuel Rommelaere, Virginie Millet, Thien-Phong Vu Manh, Thomas Gensollen, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Christophe Bourges, Bertrand Escalière, Xin Du, Yu Xia, Jean Imbert, Bruce Beutler, Yoshiakira Kanai, Bernard Malissen, Marie Malissen, Anne Tailleux, Bart Staels, Franck Galland, Philippe Naquet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4139292?pdf=render