Vaccination with LytA, LytC, or Pce of <i>Streptococcus pneumoniae</i> Protects against Sepsis by Inducing IgGs That Activate the Complement System

Vaccination with LytA, LytC, or Pce of <i>Streptococcus pneumoniae</i> Protects against Sepsis by Inducing IgGs That Activate the Complement System

The emergence of non-vaccine serotypes of <i>Streptococcus pneumoniae</i> after the use of vaccines based in capsular polysaccharides demonstrates the need of a broader protection vaccine based in protein antigens and widely conserved. In this study, we characterized three important viru...

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Bibliographic Details
Main Authors: Bruno Corsini, Leire Aguinagalde, Susana Ruiz, Mirian Domenech, Jose Yuste
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
<i>S. pneumoniae</i>
vaccine protein
LytA
LytC
Pce
cell wall hydrolases
Online Access:https://www.mdpi.com/2076-393X/9/2/186

Internet

https://www.mdpi.com/2076-393X/9/2/186

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