Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics approaches

Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics approaches

There has been progressive improvement in immunoinformatics approaches for epitope-based peptide design. Computational-based immune-informatics approaches were applied to identify the epitopes of SARS-CoV-2 to develop vaccines. The accessibility of the SARS-CoV-2 protein surface was analyzed, and he...

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Bibliographic Details
Main Authors: Saigha Marriam, Muhammad Sher Afghan, Mazhar Nadeem, Muhammad Sajid, Muhammad Ahsan, Abdul Basit, Muhammad Wajid, Sabeen Sabri, Imran Zafar, Summya Rashid, Sheikh Arslan Sehgal, Dalal Hussien M. Alkhalifah, Wael N. Hozzein, Kow-Tong Chen, Rohit Sharma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SARS-CoV-2
3CL pro
CTL epitopes
immunoinformatics
peptide-based vaccine
computational immunology
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134802/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134802/full

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