Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs

Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs

Background: Data regarding antimicrobial pharmacokinetics (PK) in critically ill dogs are lacking and likely differ from those of healthy dogs. The aim of this work is to describe a population PK model for intravenous (IV) amoxicillin–clavulanic acid (AMC) in both healthy and sick dogs and to simula...

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Bibliographic Details
Main Authors: Maria D. Vegas Cómitre, Stefano Cortellini, Marc Cherlet, Mathias Devreese, Beatrice B. Roques, Alain Bousquet-Melou, Pierre-Louis Toutain, Ludovic Pelligand
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Veterinary Science
Subjects:
antimicrobial
MIC
clinical breakpoint
Augmentin
ICU
VetCast
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.770202/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.770202/full

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