Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Abstract Heparan sulfate (HS) interacts with a broad spectrum of inflammatory cytokines, thereby modulating their biological activities. It is believed that there is a structural‐functional correlation between each protein and sugar sequences in the HS polysaccharides, however, the information in th...

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Bibliographic Details
Main Authors: Dr. Mingjia Yu, Dr. Tianji Zhang, Prof. Dr. Jin‐ping Li, Prof. Dr. Yingxia Tan
Format: Article
Language:English
Published: Wiley-VCH 2021-10-01
Series:ChemistryOpen
Subjects:
Online Access:https://doi.org/10.1002/open.202100135