Fractalkine/CX3CR1 Contributes to Endometriosis-Induced Neuropathic Pain and Mechanical Hypersensitivity in Rats

Fractalkine/CX3CR1 Contributes to Endometriosis-Induced Neuropathic Pain and Mechanical Hypersensitivity in Rats

Pain is the most severe and common symptom of endometriosis. Its underlying pathogenetic mechanism is poorly understood. Nerve sensitization is a particular research challenge, due to the limitations of general endometriosis models and sampling nerve tissue from patients. The chemokine fractalkine (...

Full description

Bibliographic Details
Main Authors: Zhiming Liu, Sisi Chen, Chunping Qiu, Yaqiong Sun, Wenzhi Li, Jie Jiang, Jun-Ming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
endometriosis
fractalkine
neuropathic pain
inflammation
microglia
peripheral hyperalgesia
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00495/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00495/full

Similar Items