Carrier-free supramolecular nanoassemblies of pure LSD1 inhibitor for effective anti-tumor therapy

The LSD1 protein is an oxidase that regulates protein methylation, which regulates gene expression and triggers tumors. Previously, inhibiting LSD1 has been found to be an effective treatment strategy for opposing tumors caused by overexpression of LSD1. Our recent study found that compound 17i was...

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Bibliographic Details
Main Authors: Boao Li, Xiangyu Zhang, Jibin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1012882/full