Kidney protective effect of sitagliptin in 5-fluorouracil-challenged rats
The possible protective effect of sitagliptin (SIT) against nephrotoxicity induced by a single dose 5-fluorouracil (5-FU) (150 mg/kg, i.p.) was investigated in rats. SIT treatment (5 and 10 mg/kg/day, p.o.) was given for 7 days, starting 5 days before 5-FU administration. Both SIT doses caused signi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2024-02-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/114441/download/pdf/ |