Kidney protective effect of sitagliptin in 5-fluorouracil-challenged rats

Kidney protective effect of sitagliptin in 5-fluorouracil-challenged rats

The possible protective effect of sitagliptin (SIT) against nephrotoxicity induced by a single dose 5-fluorouracil (5-FU) (150 mg/kg, i.p.) was investigated in rats. SIT treatment (5 and 10 mg/kg/day, p.o.) was given for 7 days, starting 5 days before 5-FU administration. Both SIT doses caused signi...

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Bibliographic Details
Main Authors:	Ahmed Hassan Al-Ghamdi, Mervat Z. Mohamed, Rabei M. Elbadry, Amr A. Fouad
Format:	Article
Language:	English
Published:	Pensoft Publishers 2024-02-01
Series:	Pharmacia
Online Access:	https://pharmacia.pensoft.net/article/114441/download/pdf/

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