Low T Cell Responsiveness in the Early Phase of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients

Low T Cell Responsiveness in the Early Phase of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients

Kidney transplant (KT) recipients are at increased risk of developing severe forms of COVID-19. Little is known about the immunological mechanisms underlying disease severity in these patients receiving T-cell targeting immunosuppressive drugs. We investigated the relationship between T cell respons...

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Bibliographic Details
Main Authors: Marion Cremoni, Sébastien Cuozzo, Emanuela Martinuzzi, Susana Barbosa, Nadia Ben Hassen, Filippo Massa, Elisa Demonchy, Matthieu Durand, Olivier Thaunat, Vincent Esnault, Moglie Le Quintrec, Sophie Caillard, Nicolas Glaichenhaus, Antoine Sicard
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
kidney transplantation
COVID-19
SARS-CoV-2
T lymphocytes
immune responsiveness
Online Access:https://www.mdpi.com/1999-4915/14/3/542

Internet

https://www.mdpi.com/1999-4915/14/3/542

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