TetR-family transcription factors in Gram-negative bacteria: conservation, variation and implications for efflux-mediated antimicrobial resistance

TetR-family transcription factors in Gram-negative bacteria: conservation, variation and implications for efflux-mediated antimicrobial resistance

Abstract Background TetR-family transcriptional regulators (TFTRs) are DNA binding factors that regulate gene expression in bacteria. Well-studied TFTRs, such as AcrR, which regulates efflux pump expression, are usually encoded alongside target operons. Recently, it has emerged that there are many T...

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Bibliographic Details
Main Authors: A. L. Colclough, J. Scadden, J. M. A. Blair
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Genomics
Subjects:
TetR-family
Regulation
Antimicrobial resistance
Conservation
Online Access:http://link.springer.com/article/10.1186/s12864-019-6075-5

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http://link.springer.com/article/10.1186/s12864-019-6075-5

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