The Antigenic Topology of Norovirus as Defined by B and T Cell Epitope Mapping: Implications for Universal Vaccines and Therapeutics

Human norovirus (HuNoV) is the leading cause of acute nonbacterial gastroenteritis. Vaccine design has been confounded by the antigenic diversity of these viruses and a limited understanding of protective immunity. We reviewed 77 articles published since 1988 describing the isolation, function, and...

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Bibliographic Details
Main Authors: Jessica M. van Loben Sels, Kim Y. Green
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/5/432