In silico prediction of high-resolution Hi-C interaction matrices

Existing computational approaches to predict long-range regulatory interactions do not fully exploit high-resolution Hi-C datasets. Here the authors present a Random Forests regression-based approach to predict high-resolution Hi-C counts using one-dimensional regulatory genomic signals.

Bibliographic Details
Main Authors: Shilu Zhang, Deborah Chasman, Sara Knaack, Sushmita Roy
Format: Article
Language:English
Published: Nature Portfolio 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13423-8