Defining the Metabolic Pathways and Host-Derived Carbon Substrates Required for <named-content content-type="genus-species">Francisella tularensis</named-content> Intracellular Growth

Defining the Metabolic Pathways and Host-Derived Carbon Substrates Required for <named-content content-type="genus-species">Francisella tularensis</named-content> Intracellular Growth

ABSTRACT Francisella tularensis is a Gram-negative, facultative, intracellular bacterial pathogen and one of the most virulent organisms known. A hallmark of F. tularensis pathogenesis is the bacterium’s ability to replicate to high densities within the cytoplasm of infected cells in over 250 known...

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Bibliographic Details
Main Authors: Lauren C. Radlinski, Jason Brunton, Shaun Steele, Sharon Taft-Benz, Thomas H. Kawula
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
Francisella tularensis
GdhA
GlpA
carbon metabolism
intracellular pathogen
Online Access:https://journals.asm.org/doi/10.1128/mBio.01471-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01471-18

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